Showing 44 results

Authority record
Holmes, Kenneth Charles
DE-EMBL ID-P-HOL01 · Person · 1934/

Holmes was born in London, GB. He attended St John's College, Cambridge from 1952 to 1955, obtaining a Bachelor's degree. He then moved on to the University of London, Birkbeck College where he worked on the structure of the tobacco virus. His dissertation was entitled "X-ray diffraction studies on tobacco mosaic virus and related substances." During his time at Birkbeck, he worked with Rosalind Franklin, Aaron Klug and John Desmond Bernal. In 1960 and 1961, Holmes was a Research Associate in Pathology The Children's Hospital, Boston, USA and Children's Cancer Research Foundation where he worked with Carolyn Cohen on muscle structure. In 1962, he moved to the Laboratory of Molecular Biology in Cambridge, GB and in 1968 he moved to the Max Planck Institute for Medical Research in Heidelberg, DE where he continued working on muscle physiology and established the Department of Biophysics. (In 2019, this is called the Department of Biomolecular Mechanisms.) Holmes was also the Head of the EMBL Hamburg site at DESY in Hamburg, DE from 1975 to 1976. Between 1971 and 1999, Holmes was also professor of Biophysics at the University of Heidelberg, DE.

IBA Heidelberg
DE-EMBL IB-IBA01 · Institutional body · 2013/2022

IBA Heidelberg is a German Architecture Exhibition in the city of Heidelberg, DE, from 2013 to 2022. Its theme is "Wissen | schafft | Stadt" (Knowledge | makes | City", a play on word on "Wissenschaft" which means "science."

Kafatos, Fotis Constantine
DE-EMBL ID-P-KAF01 · Person · 1940-04-16/2017-11-18

Fotis Constantine Kafatos was born on 16 April 1940 in Heraklion, Crete, GR. He completed his primary and secondary education there (Lyceum “Korais”). In 1959, he went to study zoology at Cornell University (Ithaca, NY, US) on a scholarship from Anne Gruner Schlumberger. He graduated with an AB (High Honors) one year early in 1961, having worked with Thomas Eisner, a pioneer of chemical ecology.

In 1961, Kafatos went to Harvard University (Cambridge, MA, US) and obtained an MA in 1962 and a PhD in 1965. His doctoral thesis was entitled “The escape of moths from the cocoon: biochemical, physiological, morphological, and developmental studies” and was advised by Dr. Carroll Milton Williams. Kafatos stayed on at Harvard as an Instructor of Biology (1965), Assistant Professor of Biology (1965-1969) and then Professor of Biology (1969-1994). During his tenure at Harvard, he divided his time with Greece, holding part-time faculty positions at the University of Athens (1972-1982) and the University of Crete (1982-1993). He also founded and headed the Institute of Molecular Biology and Biotechnology, Research Centre of Crete (1982-1993).

During his time in the United States, Kafatos was among the first to apply molecular biology methods to the study of animal development. In particular, he contributed to the development of the complementary DNA (cDNA) synthesis, cloning and sequencing, and the dot-blot method for detecting, analyzing, and identifying proteins.

In 1993, Kafatos became the third Director General of the European Molecular Biology Laboratory (EMBL), succeeding Lennart Philipson in the post. Under his stewardship, the Monterotondo Outstation (now known as EMBL Rome), focusing on mouse biology, was opened (1999) on the Adriano Buzzati-Traverso Campus of the Consiglio Nazionale delle Ricerche (CNR).

During his directorship, Kafatos continued to carry out research. He studied, in particular, malaria and its major vector, Anopheles gambiae. This work led to the sequencing of the A. gambiae genome in 2002 and opened new avenues of study regarding the Plasmodium (malaria parasite) and its interactions with its host.

In 2005, after his tenure at EMBL ended, Kafatos moved to Imperial College, London, GB, where he held the Chair of Insect Immunogenomics. In December 2005, Kafatos was elected the first chairman of the European Research Council (ERC), which was launched in 2007. In this role, Kafatos was able to support excellent, investigator-initiated fundamental European research.

In 2007, he also became an Adjunct Professor of Immunology and Infectious Diseases at the Harvard School of Public Health.

Kafatos died on 2017-11-18 in Crete.

Karsenti, Éric
DE-EMBL ID-P-KAR01 · Person · 1948-09-10/

Eric Karsenti was born in Paris (FR). After growing up in Paris, he attended the University of Paris (becoming the University Paris-VII in 1971) between 1967 and 1972, receiving a degree in sciences. Between 1972 and 1979, he carried out doctoral research in immunocytochemistry at the Institut Pasteur. He was awarded a doctorate (thèse dÉtat) in 1979 for his thesis entitled "Le rôle de la membrane plasmique et du cytosquelette dans la stimulation des lymphocytes par la Concanavaline A: recherche d'interactions entre le cytosquelette, la membrane plasmique et le génôme." In 1976, he had been recruited by the CNRS (Centre national de la recherche scientifique). Between 1979 and 1981, he worked at the Institut Pasteur as a researcher in cell and molecular biology, before taking up a postdoctoral position at the University of California, San Francisco (1981-1984). He then worked at the CNRS Centre for Experimental Cytology (Centre de cytologie expérimentale) in Paris (1984-1985) before moving to EMBL in Heidelberg in 1985.

Working in the Cell Biology Programme, Karsenti’s group researched the microtubules’ organization during the cell cycle. From 1994 to 1997, jointly with Christian Boulin, he is the programme coordinator for the Physical Instrumentation/Cell Biophysics Programme (then the Cell Biophysics Programme from 1995 to 1997). In 1998, the Cell Biophysics Programme became the Cell Biology and Biophysics Programme, and Karsenti became its programme coordinator until 2009. (In 2009, he shared this position with Jan Ellenberg.) In 2010, he became a Senior Scientist at EMBL and in 2014, Karsenti became a Visiting Scientist at EMBL.

During his time at EMBL, Karsenti’s research continued to focus on the organization of the cell during its cycle.

Between 2000 and 2003, he was also the director of the Institut Jacques Monod in Paris.

In 2009, Karsenti began working on Tara Oceans, a scientific expedition seeking to understand the key role and place of marine microorganisms in global ecosystems. Between 2009 and 2013, the expedition sailed the global ocean to gather specimens from more than 210 stations.

He was elected to EMBO in 1993, and in 2015, he was awarded the CNRS Gold Medal (Médaille d’Or du CNRS).

Mattaj, Iain William
DE-EMBL ID-P-MAT01 · Person · 1952-10-05/

Mattaj was born in St Andrews, Scotland, GB in 1952.

O'Donovan, Claire
DE-EMBL ID-P-ODO01 · Person

O'Donovan is a specialist of biocuration. She joined the EMBL Data Library in 1993, following a BSc (Hons) degree in biochemistry and a diploma in computer science from the University College Cork, Ireland. In 1994, she moved to the new EMBL site, the European Bioinformatics Institute (EMBL-EBI) in Hinxton, GB. In 2019, she is reponsible for the Metabolomics Team: her team is responsible for the MetaboLights database ( O'Donovan was also responsible for the Protein Function Content team and the biocuration of the Universal Protein Resource (UniProt) databases. These include UniProt (, the Gene Ontology Annotation project ( and the Enzyme Portal (